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  • Main Line Health Introduces Post COVID Recovery Program

    To address the complex needs of patients experiencing health issues at least 30 days following a positive COVID test result, Bryn Mawr Rehab, part of Main Line Health, is now offering personalized, multidisciplinary care for patients’ physical rehabilitation through its Post-COVID Recovery Program. The effects of COVID can last for weeks or months and some may have lifelong health issues due to COVID in what’s become known as ‘long hauler’ syndrome. Physical complications, post COVID, may include impairments in muscle strength, memory difficulties or brain fog, heart and lung capacity, pain, balance, endurance, and walking ability leading to a loss of function and independence. "We are pleased to be able to offer the Post-COVID Recovery Program to our patients as they recover from the effects of the virus and help them return to their lives. Bryn Mawr Rehab is staffed with expert physicians and therapists who can personalize an individual’s treatment plan that best addresses their health needs while providing our highest level of care,” says Donna Phillips, president of Bryn Mawr Rehab. The program’s multidisciplinary, outpatient therapeutic approach offers patients access to specialty physicians, psychologists, nutritionists and dieticians, and occupational, physical and speech therapists, highlighting Main Line Health’s continuing commitment to health care leadership within our communities. Designed to extend beyond therapy, the recovery program’s team of specialists offer services and resources to treat the patient’s customized needs. A patient may be referred to the program directly by their primary care physician or specialist provider or they may require an evaluation by a physiatrist (doctor of physical medicine and rehabilitation) to assess their overall needs that’s followed by an individualized therapy plan. Mithra Maneyapanda, MD, a physician at Bryn Mawr Rehab involved with the development of the program, says the resources and therapies offered to patients allow them to focus on areas where more recovery may be needed. “Our care team provides specialized support and therapies that are individualized to meet the needs of our patients who are recovering from COVID with dedicated, compassioned care,” notes Dr. Maneypanda.

  • Fox Chase Cancer Center added to ongoing Trial for Ewing Sarcoma and FET -Rearranged Sarcomas

    PHILADELPHIA (July 13, 2021)– Salarius Pharmaceuticals, Inc. (Nasdaq: SLRX), a clinical-stage biopharmaceutical company developing potential new medicines for patients with pediatric cancers, solid tumors, and other cancers, announced today that Fox Chase Cancer Center in Philadelphia, PA, has been added as an active trial site for the dose-expansion stage of the ongoing clinical trial evaluating the company’s lead drug candidate, seclidemstat, in patients with relapsed or refractory Ewing sarcoma and advanced FET-rearranged sarcomas. The addition of Fox Chase expands to nine the number of active sites participating in the open label trial intended to assess seclidemstat at the recommended Phase 2 dose (RP2D). Patient recruitment is now underway at all sites, and the first patients in the dose-expansion stage of the clinical trial have been dosed. Seclidemstat is a novel, oral, reversible inhibitor of lysine-specific histone demethylase 1 (LSD1), an enzyme that has been shown to play a key role in the development and progression of several cancers. Per the amended protocol, the trial’s dose-expansion stage now includes three patient arms. The first arm will enroll up to 30 patients with Ewing sarcoma, a rare and deadly pediatric bone cancer, and will investigate seclidemstat in combination with topotecan and cyclophosphamide, a commonly used second- and third- line chemotherapy regimen. Salarius believes data released during ASCO 2021 demonstrated synergy in an Ewing sarcoma cell line when seclidemstat was used in combination with topotecan and cyclophosphamide. Salarius believes this treatment combination and its use as a second- and third-line therapy could greatly expand the addressable patient population for seclidemstat and improve outcomes by allowing physicians to use seclidemstat earlier in the Ewing sarcoma continuum of care. The trial’s second patient arm will investigate seclidemstat as a single agent in up to 15 patients with myxoid liposarcoma. The third patient arm will investigate seclidemstat as a single agent in up to 15 patients with select sarcomas that share a biology similar to Ewing sarcoma, also referred to as FET-rearranged or Ewing-related sarcomas. In data released at ASCO 2021, a subset of patients with advanced FET-rearranged sarcomas treated with single-agent seclidemstat resulted in stable disease (SD) and prolonged time to progression (TTP) which Salarius believes suggests disease control, a clinically relevant endpoint for soft tissue sarcomas. All patient arms are designed to evaluate safety and efficacy endpoints in patients with advanced disease. Salarius expects to report data in 2022 and provide earlier updates if possible. “We are excited to be working with Salarius and look forward to exploring the potential of seclidemstat and its ability to inhibit the LSD1 enzyme,” stated Johnathan Whetstine, Ph.D., Director, Cancer Epigenetics Institute (CEI), Fox Chase Cancer Center. “Based on our extensive research into the epigenetic causes of cancer, we believe LSD1 inhibition holds great promise in the treatment of many cancers. We believe data from preclinical studies using Ewing sarcoma cell lines has demonstrated the molecule’s ability to hit two aspects of the enzyme simultaneously. This, added to clinical data showing drug activity across Ewing and other sarcomas, support the further exploration of seclidemstat in these high unmet need patient populations.” Dr. Whetstine is a consultant to Salarius and has also served in an advisory capacity. The recently founded CEI at Fox Chase is a national hub for epigenetics study and collaboration focused on mechanisms promoting cancer and therapeutic resistance. Its mission is to facilitate academic-to-industry and academic-to-academic partnerships with the goal of promoting discovery in cancer epigenetics. David Arthur, CEO of Salarius Pharmaceuticals, stated, “Our goal is to make a difference in the lives of patients fighting cancer, and we believe the data we have released to date has been compelling. To now be working with a cancer research center of the caliber of Fox Chase Cancer Center further affirms the potential of seclidemstat to have a meaningful impact on the treatment of Ewing sarcoma and other cancers. We look forward to providing additional updates throughout 2021.” Trial enrollment at Fox Chase will be led by Margaret von Mehren, M.D., Chief of Sarcoma Oncology. In addition to Fox Chase, active clinical trial site locations include, Johns Hopkins All Children’s Hospital in St. Petersburg, FL; Children’s Hospital of Los Angeles in Los Angeles, CA; Moffitt Cancer Center in Tampa, FL; Dana-Farber Cancer Institute in Boston, MA; MD Anderson Cancer Center in Houston, TX; Nationwide Children’s Hospital in Columbus, OH; Memorial Sloan Kettering Cancer Center in New York City; and the Sarcoma Oncology Center in Santa Monica, CA.

  • What are some of the challenges and rewards of treating pediatric patients?

    My first exposure to ophthalmology as a medical student was in pediatric retina, and I never looked back. There are many challenges, yet even more rewards, in treating children with retinal conditions. The surgeries are technically challenging and require extreme precision. Pediatric retinal surgeries require creativity and thinking outside the box, and the usual tenets of adult surgery can take you down the wrong path. Not only are the eyes smaller, but the anatomic proportions are different, and you’re working with a whole different set of diseases. Also, not only are you treating the child in front of you, but the parents require healing as well. The rewards are many. Being able to diagnose and treat genetic conditions for an entire family can save the vision of generations to come, or telling a mother that her baby will be able to see - there’s nothing better than that. At Wills Eye Hospital and Mid Atlantic Retina, we take care of a tremendous volume of complex surgical patients, both adults and children. My partners and I work with a world class team dedicated to one singular mission: to save vision. From the Desk of Dr. Yoshihiro Yonekawa Dr. Yoshihiro Yonekawa is an adult and pediatric retina specialist. He received his MD with honors from Weill Cornell Medical College, where he was recognized with the Edward Norton Award in Ophthalmology and grants from Fight for Sight and the National Eye Institute. He completed his ophthalmology residency at Harvard Medical School, and received many awards for his clinical and research expertise, including those from the American Academy of Ophthalmology (AAO). Dr. Yonekawa subsequently underwent specialized fellowship training in adult and pediatric retina surgery at Associated Retinal Consultants, William Beaumont Hospital. He received prestigious national awards during fellowship from the Heed Ophthalmic Foundation, Ronald G. Michels Foundation, and the Retina Society. Dr. Yonekawa treats both adults and children with conditions of the retina. He is committed to restoring and maintaining vision to improve the quality of life for his patients. Read more about our Ophthalmology Network

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  • Philadelphia International Medicine

    Facebook Instagram YouTube LinkedIn Twitter WeChat Connecting You To The Leading Healthcare Specialists In Philadelphia MAKE APPOINTMENT Learn more about our new Premier Health Program here City of Medicine Philadelphia International Medicine (PIM) provides international patients and physicians with access to an unmatched network of world-renowned doctors, surgeons and hospitals that deliver personalized medical, surgical and rehabilitative care ranked among the best in the world in person or from the comfort of your home. Meet Philadelphia Stories of Hope “I remember that everybody at PHL Medicine and Thomas Jefferson Hospital would tell us: Mateo and your health are our priorities, we’ll solve everything related to paperwork or insurance. I always counted on their support. They made the whole situation easier for us,” Meet our patients In Philadelphia, it's easy to find the best healthcare. We'll connect you. Our Network LEARN MORE LEARN MORE LEARN MORE LEARN MORE LEARN MORE LEARN MORE LEARN MORE LEARN MORE LEARN MORE LEARN MORE VIEW ALL OF OUR NETWORK HOSPITALS Our Specialties Cardiology Icon Cardiology VIEW MORE Neurology Neurology Icon VIEW MORE Oncology Oncology Icon VIEW MORE Rehabilitation Rehabilitation Icon VIEW MORE Ophthalmology Ophthalmology Icon VIEW MORE Orthopedics Orthopedics Icon VIEW MORE VIEW ALL OF OUR SPECIALTIES MAKE APPOINTMENT

  • Insurance | Philadelphia International Medicine

    Welcome to Philadelphia International Medicine Thank you for taking the time to learn more about Philadelphia International Medicine! By joining our network you are joining an unmatched international network of world-renowned doctors, surgeons and hospitals that deliver personalized care ranked among the best in the world. It’s easy to find access to the highest quality healthcare with services from our 10 partner networks encompassing over 100 specialties. Philadelphia International Medicine supports our patients by pairing them with the most effective medical services possible through an array of top tier physicians, surgeons, and programs. Patient support does not end at top of the line care, patients and their families are also provided with proper accommodation arrangements and information on the surrounding area. Philadelphia International Medicine also maintains efforts in empowering international governments and hospital administrators to establish world class hospitals that address local patient’s needs with the highest quality facilities and care. A message from our CEO PIM's Concierge Services Our concierge service brings the comforts and luxuries of home to your medical treatment. Sourcing a favorite food, comfortable accommodations, or finding someone who speaks your language are just a few of the ways we make your treatment a positive, restorative experience. New Philadelphia Washington Where is PIM? Philadelphia New York Washington DC 15 minute drive from Philadelphia International Airport Philadelphia International Airport Current Available International Flights to/from Philadelphia *As of July 2021 (please visit PHL.org for the latest flight information) Airline Destination Airport Flag Air Canada Toronto Pearson International Airport Air Canada Montréal–Trudeau International Airport American Airlines Amsterdam Airport Schiphol American Airlines Skyport - Bermuda L. F. Wade International Airport American Airlines Toronto Pearson International Airport American Airlines Montréal–Trudeau International Airport American Airlines Athens International Airport Page 1 of 2 experience LUXURY AT AN AFFORDABLE PRICE *Our Programs Philadelphia International Medicine Physician Bios I'm a paragraph. Click here to add your own text and edit me. It's easy. Physician One Pagers *PIM Regional Network Hospitals I'm a paragraph. Click here to add your own text and edit me. It's easy. Hospital Factsheet Premier Health Program I'm a paragraph. Click here to add your own text and edit me. It's easy. Premier Health Brochure Discover Philadelphia The city of Philadelphia is easy to reach from any worldwide location. Once you’re here, there’s a wealth of historical resources and cultural events to enjoy during your treatment. Want to learn more? Meet Philadelphia

  • International Services | Philadelphia International Medicine

    The PIM Experience PIM Globe Icon What to Expect? Since 1999, Philadelphia International Medicine has helped patients from around the globe eliminate the guesswork, planning and anxiety of finding and connecting with doctors and hospitals ranked among the best in the world. But we also offer you something else you can’t find in a medical chart: a sense of comfort and well-being. We care for you before, during, and after your visit by making sure you’re as comfortable as possible by working tirelessly to make sure you feel at home. Healing is possible when you’re confident in your healthcare team. First Aid Kit Icon Before your Visit Collect medical records, identify the best doctors and services for the patient, schedule appointments and coordinate travel, accommodation and transportation. During your Visit Provide information about the City of Philadelphia, 24/7 phone support and phone answering service, one-on-one care management & support. Telephone Consultant Icon Hand with Heart Icon After your Visit Conduct exit interviews and facilitate follow up care if necessary. First Aid Kit Icon Before your Visit Collect medical records, identify the best doctors and services for the patient, schedule appointments and coordinate travel, accommodation and transportation. During your Visit Provide information about the City of Philadelphia, 24/7 phone support and phone answering service, one-on-one care management & support. Telephone Consultant Icon Hand with Heart Icon After your Visit Conduct exit interviews and facilitate follow up care if necessary. Concierge Services Our concierge service brings the comforts and luxuries of home to your medical treatment. Sourcing a favorite food, comfortable accommodations, or finding someone who speaks your language are just a few of the ways we make your treatment a positive, restorative experience. The international patient case manager is a professional trained to support and help you manage your medical and surgical care away from home. The international patient case manager speaks multiple languages and has access to a network of local medical support services that you may need. As your main contact person , your dedicated international case manager is here to support you through every step of patient care at Philadelphia International Medicine. Your Case Manager Will:

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